Labels:text | screenshot | black and white | black OCR: Insulin, Endogenous insulin is derived from ough which is synthesised exclusively on th lls (Fig. endoplasmic reticulum of pancreatic B ly in the 20.14). Proinsulin is cleaved enzymatic lides, B-granules of the B cells to form two p released insulin and C-peptide, both of which a otrophic into the circulation following an insu ulin into stimulus, Intracellular cleavage of pro ete and, the two peptides is usually almost con s the consequently, very little proinsulin en e B-cell circulation, even in response to intens stimulation
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